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pentobarbital will lower the extent or result of buprenorphine buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.Check Carefully (one)pentobarbital will reduce the extent or outcome of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Loss of, or diminished